MD simulations suggest important surface differences between reconstituted and circulating spherical HDL
نویسندگان
چکیده
منابع مشابه
Enhanced HDL Functionality in Small HDL Species Produced Upon Remodeling of HDL by Reconstituted HDL, CSL112
RATIONALE CSL112, human apolipoprotein A-I (apoA-I) reconstituted with phosphatidylcholine, is known to cause a dramatic rise in small high-density lipoprotein (HDL). OBJECTIVE To explore the mechanisms by which the formation of small HDL particles is induced by CSL112. METHODS AND RESULTS Infusion of CSL112 into humans caused elevation of 2 small diameter HDL fractions and 1 large diameter...
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ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 2013
ISSN: 0022-2275
DOI: 10.1194/jlr.m039206